Liverpool face Nottingham Forest later in the day, while Newcastle United host Manchester City.
Leaders Arsenal host neighbors Tottenham Hotspur in a north London derby on Sunday.
Who could be absent and who could play? Here’s the latest news from Premier League teams.
Burnley vs Chelsea: Palmer sent off
Chelsea will be without Cole Palmer, who suffered a broken toe after hitting a door in an accident at home.
Palmer has not played since September 20 due to a groin injury and was due to resume first-team training this week.
However, he will miss Chelsea’s upcoming games against Burnley, Barcelona and Arsenal.
Chelsea manager Enzo Maresca said: “Unfortunately he suffered an accident at home where he stubbed his toe. It’s not important but he won’t be back next week.”
Enzo Fernandes, Pedro Neto and Benoît Badiashile are all available, while Moises Caicedo could also feature after returning safely from international duty.
Burnley manager Scott Parker is hopeful that forward Armando Broja, who was stretchered off during Albania’s game against England, will be able to feature in the match against his former club.
“Hopefully Armando will be available for the weekend. Everything about him coming back seemed very positive,” Parker said.
Liverpool vs Nottingham Forest: Wirtz, Bradley absent
Liverpool will be without Florian Wirtz and Conor Bradley for the match against Nottingham Forest.
Both suffer muscle injuries and are on the treatment table with Jeremy Frimpong.
“I don’t think Conor will take part in the next 22 days of games,” Liverpool head coach Arne Slott said. “Eventually it may happen, but unless something miraculous happens, it won’t happen within the (next) 22 days, which I’m not counting on.
“Florian should be able to play after[Forest]. It depends on what happens after that, but it shouldn’t be that long. Jeremy has been out for just as long.”
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“Obviously we miss the players and the people” – Liverpool head coach Arne Slott Ruffret
Video credit: SNTV
Goalkeeper Alisson is scheduled to return after being sidelined since September 30th.
Callum Hudson-Odoi could return to Nottingham Forest, but Chris Wood remains sidelined with a knee injury.
Manager Sean Dyche said: “Callum Hudson-Odoi has made good progress.” “He’s been on the grass with us this week so he’s definitely being considered for the squad, so that’s good news.”
Douglas Luiz (hamstring), Dillane Bakwa (tension), Ola Aina (hamstring), Oleksandr Zinchenko (groin) and Angus Gunn (knee) remain absent, while Taiwo Awoniyi is doubtful to play against Liverpool.
Brighton vs Brentford: Will Mitoma play?
Yassin Ayari, Brajan Gruda and Jack Hinshelwood are in contention for Brighton & Hove Albion, while Solly March, Adam Webster and James Milner are absent.
Kaoru Mitoma hasn’t played since September 27th due to injury and is questionable.
“It’s not easy to predict,” said coach Fabian Hürzeler.
“During the last international break, I said it was a matter of two or three weeks. But now he is approaching it. He has to deal with the pain, so it’s not a big problem. Everything is healing, so he will be fine. We have to see how he can cope with the pain.”
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Kaoru Mitoma of Brighton & Hove Albion
Image credit: Getty Images
Brentford’s Fabio Carvalho has been ruled out for the rest of the season due to an anterior cruciate ligament injury.
Josh Dasilva (knee ligament) and Antoni Mirambo (ACL) will also be unavailable against Brighton.
Wolves vs Crystal Palace: trio feature for Wolves
Wolverhampton Wanderers will be without Matt Doherty for Rob Edwards’ first game as manager.
Rodrygo Gomez and Dan Bentley are also expected to miss out.
Palace have received positive news that Marc Guehi will be available after training this week.
Guehi missed the England game with a foot injury, but manager Oliver Glasner said: “All the players are healthy.”
“Fortunately, Marc started training on Wednesday so he’s had three sessions so far and he’s doing well.”
Jean-Philippe Mateta and Eddie Nketiah are also available.
Bournemouth vs West Ham: Semenyo’s latest work
Antoine Semenyo is doubtful for Bournemouth due to an ankle injury.
Head coach Andoni Iraola said: “Antoine’s (injury) is not something new that happened when he was there (with Ghana).
“He was already suffering from an ankle injury. I don’t know if he’ll play tomorrow or not. We’ll have to wait and see.”
Justin Kluivert and Ben Gannon-Doak are out with injuries during the international break, but Tyler Adams and Adam Smith are expected to be available.
West Ham will be absent from the match as Lucas Paqueta is suspended after picking up five yellow cards.
Fulham vs Sunderland: Reinild available
Fulham striker Rodrygo Muniz will be out until February due to a thigh injury.
Sasa Lukic will also be absent due to suspension.
Reinild is expected to be available for Sunderland after returning from international duty with a minor issue.
“He suffered a slight bruise against Mozambique, but he is fit and ready for Saturday’s game,” manager Regis Le Bris said.
Newcastle vs Man City: Gordon a ‘late decision’
Newcastle manager Eddie Howe says Anthony Gordon and Tino Libramento are “very close” to returning from injury for the match against Manchester City.
Of Gordon, Howe added: “He did a good job during the break and is on track for the game. We will be making very late decisions.”
Summer signing Yoan Wissa is “close to training” with the first team, while goalkeeper Nick Pope is available after suffering a head injury in the last game.
Dan Byrne has been suspended for one game.
Man City have no new injury concerns but will be without Rodri and Mateo Kovacic.
Manager Josep Guardiola said: “Everyone is healthy except Koba and Rodri.”
Rodri is progressing well. It’s been almost three weeks since my last setback. He knows he will need time to recover mentally and physically and be consistent from now until the end.”
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“It’s great for him!” – Guardiola delighted that Haaland has qualified for the World Cup with Norway
Video credit: SNTV
Leeds vs Aston Villa: No injuries for Leeds
Leeds manager Daniel Farke says there are no injury concerns ahead of the match against Aston Villa.
“Everyone is in a good mood. We have all the players and there are no injured players,” he said.
Arsenal vs. Tottenham: Gabriel injured
Arsenal’s main defender Gabriel is expected to be out for “a number of weeks” with a thigh injury.
Manager Mikel Arteta said the Brazilian would undergo tests on Wednesday.
Riccardo Calafioli is yet to train after withdrawing from Italy’s national team due to a back problem.
Gabriel Martinelli, Victor Gokeres, Noni Madueke and Martin Odegaard are doubts with injuries.
Tottenham forward Randal Kolo Muani may play wearing a mask to protect his broken jaw.
Papu Sarr, Mohamed Kudus and Lukas Bergvall are available, but Dominic Solanke remains absent.
Manchester United vs Everton: Sesco sent off
Manchester United striker Benjamin Sesco has been ruled out due to injury.
Red Devils manager Ruben Amorim said Sesco would be out for “a few weeks” while Harry Maguire and Koby Mainu would also be unavailable for the game against Everton.
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Hargreaves explains why Manchester United ‘need Zlatan’, Sesco: ‘He’s not ready to score 30 goals’
Video credit: TNT Sports
Amorim added that Lisandro Martinez is “close to being able to play” after suffering an anterior cruciate ligament injury.
Jarrad Branthwaite will miss Everton after undergoing hamstring surgery, as will Nathan Patterson and Marlin Rolle.
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